Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 4/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545217 | 1.00 | EP300 (0.48) | EP300HSD11B1CREBBPCCR2CACNA1G | |
| SCHEMBL8550282 | 0.93 | EP300 (0.42) | EP300CREBBPCACNA1GCTSKNPSR1 | |
| SCHEMBL8550278 | 0.93 | EP300 (0.42) | EP300CREBBPCACNA1GCTSKNPSR1 | |
| SCHEMBL8548631 | 0.90 | CTSK (0.41) | EP300CREBBPCACNA1GCTSKNPSR1 | |
| SCHEMBL8548635 | 0.90 | CTSK (0.41) | EP300CREBBPCACNA1GCTSKNPSR1 | |
| SCHEMBL8545219 | 0.85 | EP300 (0.54) | EP300HSD11B1CACNA1G | |
| SCHEMBL8549403 | 0.82 | ACE (0.42) | HSD11B1CACNA1GCTSKNPSR1 | |
| SCHEMBL8549394 | 0.82 | ACE (0.42) | HSD11B1CACNA1GCTSKNPSR1 | |
| SCHEMBL8543065 | 0.81 | CTSK (0.54) | CCR2CTSKNPSR1 | |
| SCHEMBL8543070 | 0.81 | CTSK (0.54) | CCR2CTSKNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |