Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 4/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550285 | 0.93 | FKBP1A (0.49) | EP300POLBCACNA1GF2FKBP1A | |
| SCHEMBL8548639 | 0.90 | CYP3A4 (0.57) | EP300CACNA1GF2FKBP1AALDH1A1 | |
| SCHEMBL8545217 | 0.85 | EP300 (0.48) | EP300CACNA1GHSD11B1 | |
| SCHEMBL8545214 | 0.85 | EP300 (0.48) | EP300CACNA1GHSD11B1 | |
| SCHEMBL8549405 | 0.82 | CYP3A4 (0.52) | POLBCACNA1GF2FKBP1AALDH1A1 | |
| SCHEMBL8543073 | 0.81 | F2 (0.56) | POLBF2FKBP1AALDH1A1CYP3A4 | |
| SCHEMBL8544795 | 0.78 | FKBP1A (0.59) | POLBF2FKBP1AALDH1A1CYP3A4 | |
| SCHEMBL8550278 | 0.77 | EP300 (0.42) | EP300CACNA1GSMN1; SMN2 | |
| SCHEMBL8550282 | 0.77 | EP300 (0.42) | EP300CACNA1GSMN1; SMN2 | |
| SCHEMBL7452551 | 0.76 | FKBP1A (0.60) | POLBCACNA1GF2FKBP1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |