Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549394 | 1.00 | ACE (0.42) | ACECTSKNPSR1GAAALDH1A1 | |
| SCHEMBL8550278 | 0.86 | EP300 (0.42) | CTSKNPSR1GAACACNA1GSMN1; SMN2 | |
| SCHEMBL8550282 | 0.86 | EP300 (0.42) | CTSKNPSR1GAACACNA1GSMN1; SMN2 | |
| SCHEMBL8548631 | 0.84 | CTSK (0.41) | ACECTSKNPSR1GAAALDH1A1 | |
| SCHEMBL8548635 | 0.84 | CTSK (0.41) | ACECTSKNPSR1GAAALDH1A1 | |
| SCHEMBL8549405 | 0.83 | CYP3A4 (0.52) | GAAALDH1A1CACNA1GSMN1; SMN2NPC1 | |
| SCHEMBL8544794 | 0.82 | NPSR1 (0.47) | ACECTSKNPSR1GAAALDH1A1 | |
| SCHEMBL8544789 | 0.82 | NPSR1 (0.47) | ACECTSKNPSR1GAAALDH1A1 | |
| SCHEMBL8545214 | 0.82 | EP300 (0.48) | CTSKNPSR1HSD11B1CACNA1G | |
| SCHEMBL8545217 | 0.82 | EP300 (0.48) | CTSKNPSR1HSD11B1CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |