Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550282 | 1.00 | EP300 (0.42) | EP300CREBBPMEN1KMT2AHDAC1 | |
| SCHEMBL8545217 | 0.93 | EP300 (0.48) | EP300CREBBPNPSR1CACNA1GCTSK | |
| SCHEMBL8548631 | 0.93 | CTSK (0.41) | EP300CREBBPMEN1KMT2ANPSR1 | |
| SCHEMBL8545214 | 0.93 | EP300 (0.48) | EP300CREBBPNPSR1CACNA1GCTSK | |
| SCHEMBL8548635 | 0.93 | CTSK (0.41) | EP300CREBBPMEN1KMT2ANPSR1 | |
| SCHEMBL8549394 | 0.86 | ACE (0.42) | NPSR1CACNA1GCTSKGAASMN1; SMN2 | |
| SCHEMBL8549403 | 0.86 | ACE (0.42) | NPSR1CACNA1GCTSKGAASMN1; SMN2 | |
| SCHEMBL8550285 | 0.83 | FKBP1A (0.49) | EP300CACNA1GSMN1; SMN2 | |
| SCHEMBL8544789 | 0.81 | NPSR1 (0.47) | NPSR1CTSKGAA | |
| SCHEMBL8544794 | 0.81 | NPSR1 (0.47) | NPSR1CTSKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |