Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544750 | 0.81 | POLB (0.45) | ALDH1A1TSHRHSD17B10SNCACYP3A4 | |
| SCHEMBL8539537 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10SNCACYP3A4 | |
| SCHEMBL14746991 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRHSD17B10SNCACYP3A4 | |
| SCHEMBL27318875 | 0.78 | SNCA (0.46) | ALDH1A1TSHRHSD17B10SNCACYP3A4 | |
| SCHEMBL7781811 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRHSD17B10SNCACYP3A4 | |
| SCHEMBL8539340 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TSHRHSD17B10CYP3A4MEN1 | |
| SCHEMBL4541319 | 0.73 | SMYD3 (0.48) | ALDH1A1TSHRHSD17B10SNCACYP3A4 | |
| SCHEMBL9683184 | 0.72 | ALDH1A1 (0.51) | ALDH1A1TSHRHSD17B10SNCACYP3A4 | |
| SCHEMBL2363794 | 0.72 | ALDH1A1 (0.63) | ALDH1A1TSHRHSD17B10SNCACYP3A4 | |
| SCHEMBL11162218 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10SNCACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581500-B1 | Antibiotic carbapenem compounds | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5441949-A | Carbapenem antibiotic compounds | ZENECA LIMITED (GB) | 1995-08-15 | — | — | US | disclosed |
| EP-0581500-A1 | Antibiotic carbapenem compounds | ZENECA LIMITED (GB) | 1994-02-02 | — | — | EP | disclosed |