Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | PRKCI | P41743 | 2/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185211 | 0.83 | CYP3A4 (0.65) | ALDH1A1TSHRHSD17B10CYP3A4KDM4E | |
| SCHEMBL2358122 | 0.83 | CYP3A4 (0.65) | ALDH1A1TSHRHSD17B10CYP3A4KDM4E | |
| SCHEMBL8423197 | 0.82 | CYP3A4 (0.63) | ALDH1A1TSHRHSD17B10CYP3A4KDM4E | |
| SCHEMBL9471700 | 0.82 | CYP3A4 (0.63) | ALDH1A1TSHRHSD17B10CYP3A4POLB | |
| SCHEMBL2358545 | 0.82 | CYP3A4 (0.63) | ALDH1A1TSHRHSD17B10CYP3A4SNCA | |
| SCHEMBL9693524 | 0.82 | CYP3A4 (0.63) | ALDH1A1TSHRHSD17B10CYP3A4KDM4E | |
| SCHEMBL9693536 | 0.81 | CYP3A4 (0.61) | ALDH1A1TSHRHSD17B10CYP3A4SNCA | |
| SCHEMBL181049 | 0.80 | ALDH1A1 (0.60) | ALDH1A1TSHRHSD17B10KDM4ENAPRT | |
| SCHEMBL11860480 | 0.79 | CYP3A4 (0.59) | ALDH1A1TSHRHSD17B10CYP3A4KDM4E | |
| SCHEMBL8041829 | 0.79 | CYP3A4 (0.73) | ALDH1A1TSHRHSD17B10CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125807-B1 | IMIDAZO[1,2-A]PYRROLO[3,2-C]PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS | UNIV LEUVEN KATH (BE) | 2011-08-03 | — | — | EP | claimed |
| US-20100093781-A1 | IMIDAZO [1, 2-A] PYRROLO [3, 2-C] PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS | UNIVERSITE D'AUVERGNE CLERMONT 1 (FR) | 2010-04-15 | — | — | US | claimed |
| EP-2125807-A2 | IMIDAZO[1,2-A]PYRROLO[3,2-C]PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS | Katholieke Universiteit Leuven (BE) | 2009-12-02 | — | — | EP | claimed |
| WO-2008070937-A2 | IMIDAZO [1, 2-A] PYRROLO [3, 2-C] PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-06-19 | — | — | WO | claimed |
| US-8404707-B2 | Imidazo [1, 2-a] pyrrolo [3, 2-c] pyridine compounds useful as pestivirus inhibitors | UNIVERSITE D'AUVERGNE CLERMONT 1 (FR) | 2013-03-26 | — | — | US | disclosed |
| EP-2125807-B1 | IMIDAZO[1,2-A]PYRROLO[3,2-C]PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS | UNIV LEUVEN KATH (BE) | 2011-08-03 | — | — | EP | disclosed |
| US-20100160304-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20100093781-A1 | IMIDAZO [1, 2-A] PYRROLO [3, 2-C] PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS | UNIVERSITE D'AUVERGNE CLERMONT 1 (FR) | 2010-04-15 | — | — | US | disclosed |
| EP-2125807-A2 | IMIDAZO[1,2-A]PYRROLO[3,2-C]PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS | Katholieke Universiteit Leuven (BE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008070937-A2 | IMIDAZO [1, 2-A] PYRROLO [3, 2-C] PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-06-19 | — | — | WO | disclosed |
| EP-1844768-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |
| US-3993656-A | BRONCHODILATOR, HYPOTENSIVES | MERCK & CO., INC. (US) | 1976-11-23 | — | — | US | disclosed |
| US-3993656-A | BRONCHODILATOR, HYPOTENSIVES | MERCK & CO., INC. (US) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160304-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | NR3C2, AGTR1, AGTR2 | ALDH1A1 1053/4885TSHR 173/4885HSD17B10 665/4885 |
| US-20100093781-A1 | IMIDAZO [1, 2-A] PYRROLO [3, 2-C] PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS | PPM1D, CDKN1A, PPM1A | ALDH1A1 1442/4885TSHR 2748/4885HSD17B10 4067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.