Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545278 | 1.00 | ELANE (0.47) | ELANECTRB1ALDH1A1USP2LMNA | |
| SCHEMBL8546638 | 0.87 | ELANE (0.45) | ELANECTRB1ALDH1A1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL10961198 | 0.83 | ELANE (0.62) | ELANECTRB1 | |
| SCHEMBL8545895 | 0.81 | ALDH1A1 (0.50) | ELANECTRB1ALDH1A1LMNA | |
| SCHEMBL6498596 | 0.81 | ELANE (0.74) | ELANECTRB1 | |
| SCHEMBL6498813 | 0.81 | ELANE (0.74) | ELANECTRB1 | |
| SCHEMBL8549933 | 0.80 | ELANE (0.44) | ELANECTRB1 | |
| SCHEMBL8545838 | 0.80 | ELANE (0.37) | ELANECTRB1ALDH1A1USP2LMNA | |
| SCHEMBL8545872 | 0.79 | ALDH1A1 (0.47) | ELANECTRB1ALDH1A1LMNA | |
| SCHEMBL10964892 | 0.77 | ELANE (0.72) | ELANECTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |