Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506692 | 0.89 | CTRB1 (0.62) | MAPTSMN1; SMN2PKMHPGDHTT | |
| SCHEMBL8476287 | 0.81 | CTRB1 (0.58) | MAPTSMN1; SMN2ACETP53ELANE | |
| SCHEMBL8545277 | 0.80 | MAPT (0.59) | MAPTSMN1; SMN2PKMHPGDHTT | |
| SCHEMBL8549764 | 0.80 | ELANE (0.47) | ACEELANECTRB1CTSSCTSK | |
| SCHEMBL8543203 | 0.77 | CTRB1 (0.57) | MAPTHPGDELANECTRB1KDM4E | |
| SCHEMBL6499875 | 0.77 | ELANE (0.67) | ELANECTRB1CTSSCTSK | |
| SCHEMBL6496223 | 0.73 | ELANE (0.72) | MAPTPKMHPGDHTTACE | |
| SCHEMBL1003555 | 0.73 | ACE (0.77) | MAPTSMN1; SMN2ACETP53CTSL | |
| SCHEMBL850438 | 0.73 | ACE (0.77) | MAPTSMN1; SMN2ACETP53CTSL | |
| SCHEMBL1486167 | 0.73 | ACE (0.77) | MAPTSMN1; SMN2ACETP53CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |