SCHEMBL854529

SCHEMBL854529

N[C@@H](Cc1ccc(NC(=O)C2CC(=O)NC(=O)N2)cc1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.42
PTGS1 P23219 3/20 0.40
ALPI P09923 1/20 0.40
PKM P14618 1/20 0.40
XIAP P98170 1/20 0.40
ITGB3 P05106 1/20 0.40
ITGAV P06756 1/20 0.40
ITGA2B P08514 1/20 0.40
CYP3A4 P08684 3/20 0.38
ALOX15 P16050 3/20 0.38
HIF1A Q16665 3/20 0.38
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 2/20 0.38
ABCB11 O95342 1/20 0.38
CHRM2 P08172 1/20 0.38
ADRA2A P08913 1/20 0.38
CHRM1 P11229 1/20 0.38
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL854528 1.00 SLC7A5 (0.42) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL21507745 0.91 ALDH1A1 (0.39) ALOX15ALDH1A1MEN1LMNAMAPT
SCHEMBL1932929 0.85 ALDH1A1 (0.36) ALOX15ALDH1A1MEN1LMNAMAPT
SCHEMBL1932933 0.85 POLB (0.38) ITGB3ITGAVALOX15ALDH1A1MEN1
SCHEMBL24324961 0.81 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2MEN1KMT2AUSP2
SCHEMBL23470065 0.80 ALDH1A1 (0.38) ALDH1A1MEN1LMNAMAPTKMT2A
SCHEMBL18986854 0.80 SLC7A5 (0.42) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL21507742 0.78 GNRHR (0.35) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL20578136 0.75 CA2 (0.43) ALDH1A1TDP1LMNAHDAC3HDAC1
SCHEMBL6575751 0.75 KMT2A (0.62) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3110828-B1 CONTINUOUS FLOW PEPTIDE SYNTHESIS UNIV SZEGEDI (HU) 2020-12-09 EP claimed
EP-3110828-A1 CONTINUOUS FLOW PEPTIDE SYNTHESIS Szegedi Tudományegyetem (HU) 2017-01-04 EP claimed
WO-2015128687-A1 CONTINUOUS FLOW PEPTIDE SYNTHESIS Szegedi Tudományegyetem (HU) 2015-09-03 WO claimed
EP-2076535-B1 RECEPTOR(SSTR2)-SELECTIVE SOMATOSTATIN ANTAGONISTS SALK INST FOR BIOLOGICAL STUDI (US) 2013-03-06 EP claimed
US-12486302-B2 Somatostatin receptor antagonist compounds and methods of using the same CDRD VENTURES INC. (CA) 2025-12-02 US disclosed
EP-4630064-A1 ALPHA EMITTER LABELLED SOMATOSTATIN RECEPTOR ANTAGONISTS Ariceum Therapeutics GmbH (DE) 2025-10-15 EP disclosed
US-20250235566-A1 TRISLINKER-CONJUGATED DIMERIC LABELING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM Medianezia GmbH (DE) 2025-07-24 US disclosed
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof RAYZEBIO, INC. (US) 2025-07-10 US disclosed
WO-2025137443-A1 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING SOMATOSTATIN RECEPTORS AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO disclosed
WO-2025137441-A1 RADIOPHARMACEUTICALS TARGETING SOMATOSTATIN RECEPTOR 2 AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO disclosed
CN-118785925-A Marker precursors and radiotracers with three or more targeting vectors for use in diagnostic nuclear medicine therapies 原子治疗有限公司 2024-10-15 CN disclosed
WO-2024121249-A1 ALPHA EMITTER LABELLED SOMATOSTATIN RECEPTOR ANTAGONISTS ARICEUM THERAPEUTICS GMBH (DE) 2024-06-13 WO disclosed
EP-2383289-A1 Receptor (SSTR2)-selective somatostatin antagonists The Salk Institute for Biological Studies (US) 2011-11-02 EP disclosed
US-7960342-B2 Side effect reduction; block receptor function so they can be used in therapy; labeled with radioactive iodine; drug screening THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2011-06-14 US disclosed
EP-2268667-A2 SOMATOSTATIN RECEPTOR 2 ANTAGONISTS Salk Institute For Biological Studies (US) 2011-01-05 EP disclosed
WO-2009129311-A2 SOMATOSTATIN RECEPTOR 2 ANTAGONISTS SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2009-10-22 WO disclosed
EP-2076535-A2 RECEPTOR(SSTR2)-SELECTIVE SOMATOSTATIN ANTAGONISTS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2009-07-08 EP disclosed
US-20080299040-A1 SOMATOSTATIN RECEPTOR 2 ANTAGONISTS SALK INSTITUTE FOR BIOLOGICAL STUDIES UNIVERSITAT BERN UNIVERSITY HOSPITAL BASEL 2008-12-04 US disclosed
US-20080260638-A1 RECEPTOR(SSTR2)-SELECTIVE SOMATOSTATIN ANTAGONISTS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2008-10-23 US disclosed
WO-2008048942-A2 RECEPTOR(SSTR2)-SELECTIVE SOMATOSTATIN ANTAGONISTS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2008-04-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080260638-A1 RECEPTOR(SSTR2)-SELECTIVE SOMATOSTATIN ANTAGONISTS SSTR5, SSTR4, SSTR3 SLC7A5 85/4885PTGS1 4381/4885ALPI 4180/4885
US-12486302-B2 Somatostatin receptor antagonist compounds and methods of using the same GPR119, SSTR5, SSTR2 SLC7A5 1032/4885PTGS1 2711/4885ALPI 918/4885
US-20250235566-A1 TRISLINKER-CONJUGATED DIMERIC LABELING PRECURSORS AND RADIOTRACERS DERIVED THEREFROM TK1, TK2, TMT1A SLC7A5 357/4885PTGS1 4069/4885ALPI 4643/4885
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof SSTR2, SSTR4, SSTR5 SLC7A5 286/4885PTGS1 4839/4885ALPI 3379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.