Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544930 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HSD17B10TSHRCYP3A4PSMD14 | |
| SCHEMBL8545120 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL11973493 | 0.78 | PSMD14 (0.68) | ALDH1A1HSD17B10PSMD14KDM4EL3MBTL1 | |
| SCHEMBL960227 | 0.77 | CYP3A4 (0.76) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL30553415 | 0.76 | KDM4E (0.51) | ALDH1A1TSHRPSMD14KDM4EL3MBTL1 | |
| SCHEMBL27214228 | 0.76 | KDM4E (0.51) | ALDH1A1TSHRPSMD14KDM4EL3MBTL1 | |
| SCHEMBL6537541 | 0.75 | CYP3A4 (0.40) | ALDH1A1HSD17B10TSHRCYP3A4MEN1 | |
| SCHEMBL5673559 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL5339693 | 0.75 | ALDH1A1 (0.77) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL23754362 | 0.74 | KDM4E (0.68) | ALDH1A1PSMD14KDM4EL3MBTL1KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581500-B1 | Antibiotic carbapenem compounds | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5441949-A | Carbapenem antibiotic compounds | ZENECA LIMITED (GB) | 1995-08-15 | — | — | US | disclosed |
| EP-0581500-A1 | Antibiotic carbapenem compounds | ZENECA LIMITED (GB) | 1994-02-02 | — | — | EP | disclosed |