Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 6/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549489 | 0.85 | SMN1; SMN2 (0.35) | TRPM8CDC7DBF4ALDH1A1HSD17B10 | |
| SCHEMBL8549517 | 0.83 | ALDH1A1 (0.39) | TRPM8CDC7DBF4ALDH1A1HSD17B10 | |
| SCHEMBL9035936 | 0.80 | ALDH1A1 (0.46) | TRPM8ALDH1A1HSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL8590103 | 0.78 | CDC7 (0.38) | CDC7DBF4ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL8590107 | 0.78 | CDC7 (0.38) | CDC7DBF4ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL8547337 | 0.77 | ALDH1A1 (0.43) | TRPM8CDC7DBF4ALDH1A1HSD17B10 | |
| SCHEMBL8545588 | 0.75 | TRPM8 (0.41) | TRPM8CDC7DBF4ALDH1A1HSD17B10 | |
| SCHEMBL8545180 | 0.75 | ALDH1A1 (0.43) | TRPM8CDC7DBF4ALDH1A1HSD17B10 | |
| SCHEMBL8550254 | 0.74 | TRPM8 (0.46) | TRPM8ALDH1A1HSD17B10SMN1; SMN2TSHR | |
| SCHEMBL8546642 | 0.73 | TRPM8 (0.40) | TRPM8ALDH1A1HSD17B10SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |