Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547009 | 1.00 | NR3C1 (0.48) | NR3C1ALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL8546496 | 0.93 | NR3C1 (0.47) | NR3C1ALOX5PTGESFFAR1FFAR4 | |
| SCHEMBL8549653 | 0.93 | LPAR1 (0.46) | NR3C1ALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL8549623 | 0.91 | NR3C1 (0.43) | NR3C1ALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL5320045 | 0.91 | PARP10 (0.44) | ALOX5PTGS1PTGS2L3MBTL1PARP10 | |
| SCHEMBL8550259 | 0.88 | PLA2G10 (0.49) | ALOX5PTGS1PTGS2L3MBTL1PARP10 | |
| SCHEMBL8550313 | 0.87 | MEN1 (0.49) | ALOX5PTGS1PTGS2L3MBTL1PARP10 | |
| SCHEMBL8545520 | 0.87 | PPIB (0.51) | ALOX5PTGS1PTGS2L3MBTL1PARP10 | |
| SCHEMBL8546552 | 0.86 | MEN1 (0.48) | ALOX5PTGS1PTGS2L3MBTL1PARP10 | |
| SCHEMBL8549400 | 0.82 | PARP10 (0.49) | ALOX5PTGS1PTGS2L3MBTL1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |