Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 1/20 | 0.51 |
| ▸ | PPID | Q08752 | 1/20 | 0.51 |
| ▸ | PPIG | Q13427 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320045 | 0.92 | PARP10 (0.44) | PPIBPPIDPPIGRAB9AL3MBTL1 | |
| SCHEMBL8550259 | 0.89 | PLA2G10 (0.49) | PPIBPPIDPPIGRAB9AL3MBTL1 | |
| SCHEMBL8545528 | 0.87 | NR3C1 (0.48) | L3MBTL1ALOX5PTGS1PTGS2PARP10 | |
| SCHEMBL8547009 | 0.87 | NR3C1 (0.48) | L3MBTL1ALOX5PTGS1PTGS2PARP10 | |
| SCHEMBL8549653 | 0.83 | LPAR1 (0.46) | L3MBTL1ALOX5PTGS1PTGS2 | |
| SCHEMBL8550313 | 0.83 | MEN1 (0.49) | RAB9AL3MBTL1SMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL8551384 | 0.82 | CRHBP (0.53) | RAB9ASMN1; SMN2NPC1LMNAALDH1A1 | |
| SCHEMBL8546552 | 0.82 | MEN1 (0.48) | L3MBTL1ALOX5PTGS1PTGS2PARP10 | |
| SCHEMBL8546496 | 0.81 | NR3C1 (0.47) | ALOX5KDM4EALDH1A1 | |
| SCHEMBL8543702 | 0.81 | ACHE (0.49) | L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045005-C | Novel bisoxadiazolidine derivative | YAMANOUCHI PHARMA CO LTD (JP) | 1999-09-08 | — | — | CN | disclosed |
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| CN-1122133-A | Novel bis-oxadiazolidine derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1996-05-08 | — | — | CN | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |