Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550313 | 0.84 | MEN1 (0.49) | PARP10ALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL8546552 | 0.83 | MEN1 (0.48) | PARP10ALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL8545528 | 0.82 | NR3C1 (0.48) | PARP10ALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL8547009 | 0.82 | NR3C1 (0.48) | PARP10ALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL5320045 | 0.82 | PARP10 (0.44) | PARP10ALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL8550341 | 0.80 | FURIN (0.44) | PARP10KCNH2 | |
| SCHEMBL8550259 | 0.79 | PLA2G10 (0.49) | PARP10ALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL8549653 | 0.79 | LPAR1 (0.46) | ALOX5PTGS1PTGS2L3MBTL1FFAR1 | |
| SCHEMBL8545520 | 0.78 | PPIB (0.51) | PARP10ALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL8545668 | 0.77 | PARP10 (0.59) | PARP10PARP15PARP2ALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |