Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.59 |
| ▸ | EGFR | P00533 | 3/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547170 | 0.87 | HTT (0.55) | HTTEGFRPIK3CDPIK3R1PDE4A | |
| SCHEMBL7511027 | 0.84 | EGFR (0.57) | HTTEGFRPDE4APDE4BPDE4C | |
| SCHEMBL8547866 | 0.84 | HTT (0.43) | HTTEGFRPIK3CDPIK3R1PDE4A | |
| SCHEMBL8544390 | 0.81 | ACHE (0.43) | HTTEGFRPDE4APDE4BPDE4C | |
| SCHEMBL8547584 | 0.81 | KDR (0.51) | HTTEGFRACHERAB9ANPC1 | |
| SCHEMBL29057185 | 0.77 | SMN1; SMN2 (0.53) | HTTEGFRPDE4APDE4BPDE4C | |
| SCHEMBL8542357 | 0.76 | RAB9A (0.58) | HTTEGFRPDE4APDE4BPDE4C | |
| SCHEMBL8079742 | 0.76 | PI4KA (0.47) | HTTEGFRPDE4APDE4BPDE4C | |
| SCHEMBL8654328 | 0.76 | ACHE (0.43) | HTTEGFRPDE4APDE4BPDE4C | |
| SCHEMBL28055911 | 0.74 | PI4KA (0.46) | HTTPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |