Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 5/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079742 | 0.98 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBHRH1 | |
| SCHEMBL8654328 | 0.81 | ACHE (0.43) | PI4KAPI4K2BPI4K2API4KBACHE | |
| SCHEMBL29057185 | 0.79 | SMN1; SMN2 (0.53) | PI4KAPI4K2BPI4K2API4KBACHE | |
| SCHEMBL8547170 | 0.79 | HTT (0.55) | PI4KAPI4K2BPI4K2API4KBACHE | |
| SCHEMBL11728330 | 0.78 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBACHE | |
| SCHEMBL28731954 | 0.75 | RAB9A (0.62) | PI4KAPI4K2BPI4K2API4KBACHE | |
| SCHEMBL11953072 | 0.75 | ALDH1A1 (0.48) | PI4KAPI4K2BPI4K2API4KBACHE | |
| SCHEMBL10752255 | 0.75 | LOXL2 (0.62) | HRH1TLR8MAPTLOXL2 | |
| SCHEMBL14157416 | 0.75 | LOXL2 (0.62) | HRH1TLR8MAPTLOXL2 | |
| SCHEMBL10757258 | 0.75 | LOXL2 (0.62) | HRH1TLR8MAPTLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104130200-B | A kind of 2-substituted-phenyl-4-aryl amine quinazoline derivant and its preparation method and application | SUN YAT-SEN UNIVERSITY (CN) | 2016-04-20 | — | — | CN | claimed |