Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8540290 | 0.99 | PKM (0.59) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8701243 | 0.94 | NPC1 (0.62) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8701279 | 0.94 | NPC1 (0.53) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9031024 | 0.93 | PKM (0.53) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8703358 | 0.90 | PKM (0.58) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8699553 | 0.89 | PKM (0.52) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8703355 | 0.87 | PKM (0.55) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8699493 | 0.87 | PKM (0.55) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8700978 | 0.83 | HPGD (0.45) | PKMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8699576 | 0.82 | NPC1 (0.53) | PKMNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |