Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545595 | 0.94 | PKM (0.59) | NPC1RAB9AMEN1KMT2APKM | |
| Hydrochloric Acid SCHEMBL8540290 | 0.93 | PKM (0.59) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL8701279 | 0.90 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL8699553 | 0.88 | PKM (0.52) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL9031024 | 0.87 | PKM (0.53) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL8703358 | 0.84 | PKM (0.58) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL8703355 | 0.82 | PKM (0.55) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL8699493 | 0.82 | PKM (0.55) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL8542041 | 0.81 | CYP19A1 (0.45) | TBXAS1 | |
| SCHEMBL8538696 | 0.81 | FAAH (0.50) | MEN1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |