Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545595 | 0.83 | PKM (0.59) | HPGDPKMTBXAS1NPC1MEN1 | |
| Hydrochloric Acid SCHEMBL8540290 | 0.82 | PKM (0.59) | PKMTBXAS1NPC1MEN1RAB9A | |
| SCHEMBL8695802 | 0.80 | CYP19A1 (0.43) | TBXAS1CYP19A1 | |
| SCHEMBL8701279 | 0.79 | NPC1 (0.53) | HPGDSMN1; SMN2PKMTBXAS1NPC1 | |
| SCHEMBL8541319 | 0.78 | HPGD (0.50) | HPGDSMN1; SMN2TBXAS1NPC1ALDH1A1 | |
| SCHEMBL8546276 | 0.78 | CPB1 (0.55) | HPGDSMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL8540312 | 0.77 | GRIN2B (0.55) | TBXAS1NPC1KDM4EALDH1A1TDP1 | |
| SCHEMBL8701243 | 0.77 | NPC1 (0.62) | HPGDPKMTBXAS1NPC1MEN1 | |
| SCHEMBL9031024 | 0.77 | PKM (0.53) | SMN1; SMN2PKMNPC1MEN1RAB9A | |
| SCHEMBL8700975 | 0.77 | HPGD (0.45) | HPGDSMN1; SMN2PKMNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |