SCHEMBL8699493

SCHEMBL8699493

CSc1ccc(CCC(=O)N2CCCCC2CCn2ccnc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.55
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
BLM P54132 1/20 0.40
TBXAS1 P24557 5/20 0.39
QPCT Q16769 1/20 0.38
CYP19A1 P11511 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8703358 0.89 PKM (0.58) PKMKMT2AMEN1NPC1RAB9A
SCHEMBL8545595 0.87 PKM (0.59) PKMKMT2AMEN1NPC1RAB9A
SCHEMBL8703355 0.87 PKM (0.55) PKMKMT2AMEN1NPC1RAB9A
Hydrochloric Acid SCHEMBL8540290 0.86 PKM (0.59) PKMKMT2AMEN1NPC1RAB9A
SCHEMBL8540293 0.82 CPB1 (0.44) TBXAS1QPCT
SCHEMBL8701279 0.82 NPC1 (0.53) PKMKMT2AMEN1NPC1RAB9A
SCHEMBL8701243 0.82 NPC1 (0.62) PKMKMT2AMEN1NPC1RAB9A
SCHEMBL9031024 0.81 PKM (0.53) PKMKMT2AMEN1NPC1RAB9A
SCHEMBL8699300 0.81 CYP19A1 (0.44) PKMTBXAS1QPCTCYP19A1
SCHEMBL8699553 0.77 PKM (0.52) PKMKMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5741800-A ANTIINFLAMMATORY AGENT, ANTIALLERGENS KNOLL AKTIENGESELLACHAFT (DE) 1998-04-21 US disclosed