Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | CPA3 | P15088 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367484 | 0.77 | LMNA (0.44) | TSHRSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9548337 | 0.75 | CPA3 (0.56) | FFAR1CPA3 | |
| SCHEMBL28592638 | 0.73 | TSHR (0.46) | TDP1L3MBTL1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL31383447 | 0.71 | PTGER1 (0.43) | FFAR1CYSLTR2CYSLTR1PTGER1PTGER4 | |
| SCHEMBL8053590 | 0.71 | KMT2A (0.50) | TDP1L3MBTL1MEN1KMT2AKDM4C | |
| SCHEMBL30873948 | 0.71 | NPSR1 (0.57) | POLBFFAR1PTGER1PTGER4PTGER3 | |
| SCHEMBL1450886 | 0.71 | NPSR1 (0.57) | POLBFFAR1PTGER1PTGER4PTGER3 | |
| SCHEMBL9544466 | 0.70 | CYP1A2 (0.47) | MEN1KMT2APOLBFFAR1CRHBP | |
| SCHEMBL8765867 | 0.70 | CYP1A2 (0.47) | MEN1KMT2APOLBFFAR1CRHBP | |
| SCHEMBL725597 | 0.70 | LMNA (0.48) | MEN1KMT2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-A1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033175-A1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-10-24 | — | — | WO | disclosed |