Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545596 | 0.77 | TDP1 (0.39) | MEN1KMT2ACRHBPCRHR2POLB | |
| SCHEMBL9548337 | 0.77 | CPA3 (0.56) | — | |
| SCHEMBL8765867 | 0.74 | CYP1A2 (0.47) | LMNAMEN1KMT2AMAPTCRHBP | |
| SCHEMBL9544466 | 0.74 | CYP1A2 (0.47) | LMNAMEN1KMT2AMAPTCRHBP | |
| SCHEMBL27368421 | 0.74 | MTNR1A (0.48) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL27369263 | 0.74 | MTNR1A (0.48) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL6971997 | 0.72 | KDM4E (0.46) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20543888 | 0.72 | SCN9A (0.50) | LMNAGAAMEN1KMT2AMAPT | |
| SCHEMBL362209 | 0.72 | LMNA (0.59) | LMNAPOLBSMN1; SMN2HPGD | |
| SCHEMBL29590071 | 0.72 | LMNA (0.59) | LMNAPOLBSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1063430-C | Ethanolamine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-03-21 | — | — | CN | disclosed |
| CN-1084846-A | Ethanolamine derivant | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-04-06 | — | — | CN | disclosed |