Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104783 | 0.76 | SLC6A2 (0.46) | ALOX15CYP3A4TDP1SLC6A2SLC6A4 | |
| SCHEMBL28282147 | 0.73 | ALDH1A1 (0.44) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8545887 | 0.72 | ALOX15 (0.37) | MAPTALDH1A1ALOX15HTTNPSR1 | |
| SCHEMBL27845164 | 0.72 | ALDH1A1 (0.50) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7630645 | 0.70 | SLC6A2 (0.48) | ALDH1A1TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31517195 | 0.70 | SLC6A2 (0.48) | ALDH1A1TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11900726 | 0.70 | CXCR2 (0.51) | MAPTALDH1A1LMNAMEN1KMT2A | |
| Formic Acid SCHEMBL28259321 | 0.68 | SLC6A2 (0.39) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL2904304 | 0.68 | ALDH1A1 (0.42) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11901586 | 0.66 | MAPT (0.50) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698014-B1 | 3-PHENYLUREIDO-1,5-BENZODIAZEPINE-DIONES USEFUL AS GASTRIN OR CCK ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 1998-07-22 | — | — | EP | disclosed |
| EP-0698014-A1 | 3-PHENYLUREIDO-1,5-BENZODIAZEPINE-DIONES USEFUL AS GASTRIN OR CCK ANTAGONISTS | GLAXO S.p.A. (IT) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994025444-A1 | 3-PHENYLUREIDO-1,5-BENZODIAZEPINE-DIONES USEFUL AS GASTRIN OR CCK ANTAGONISTS | GLAXO SPA (IT) | 1994-11-10 | — | — | WO | disclosed |