Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545771 | 0.72 | MAPT (0.40) | ALOX15MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL2904304 | 0.63 | ALDH1A1 (0.42) | ALOX15MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL3895691 | 0.61 | ALDH1A1 (0.46) | ALOX15MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL27909664 | 0.60 | NOS3 (0.33) | — | |
| SCHEMBL6855456 | 0.60 | MAPT (0.47) | ALOX15MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL28916357 | 0.59 | NOS3 (0.35) | NPSR1 | |
| SCHEMBL28282147 | 0.59 | ALDH1A1 (0.44) | ALOX15MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL28883156 | 0.59 | ALDH1A1 (0.44) | ALOX15MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL18109165 | 0.58 | ALDH1A1 (0.43) | ALOX15MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL104783 | 0.58 | SLC6A2 (0.46) | ALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698014-B1 | 3-PHENYLUREIDO-1,5-BENZODIAZEPINE-DIONES USEFUL AS GASTRIN OR CCK ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 1998-07-22 | — | — | EP | disclosed |