Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.75 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548009 | 0.91 | F2 (0.64) | F2PKMNAMPTPGRNR3C1 | |
| SCHEMBL8547842 | 0.89 | F2 (0.67) | F2NAMPTPGRNR3C1MAPT | |
| SCHEMBL7364438 | 0.87 | F2 (0.67) | F2PKMPGR | |
| SCHEMBL8548264 | 0.86 | PKM (0.57) | F2PKMNAMPTPGRNR3C1 | |
| SCHEMBL8546878 | 0.85 | F2 (1.00) | F2 | |
| SCHEMBL8542813 | 0.83 | F2 (0.73) | F2PKMNR3C1MAPT | |
| SCHEMBL8543114 | 0.81 | F2 (0.62) | F2PKMNR3C1MAPT | |
| SCHEMBL7332305 | 0.77 | PGR (0.55) | PGRNR3C1MAPT | |
| SCHEMBL27336362 | 0.76 | GAA (0.52) | F2PGRNR3C1MAPT | |
| SCHEMBL8548218 | 0.76 | NAMPT (0.56) | F2PKMNAMPTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |