Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 3/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548218 | 0.86 | NAMPT (0.56) | PKMF2NAMPTMEN1KMT2A | |
| SCHEMBL8545802 | 0.86 | F2 (0.75) | PKMF2NAMPTPGRNR3C1 | |
| SCHEMBL7334051 | 0.81 | MEN1 (0.54) | PKMNAMPTPGRMEN1KMT2A | |
| SCHEMBL27336362 | 0.81 | GAA (0.52) | F2PGRMEN1KMT2AESR1 | |
| SCHEMBL8548009 | 0.78 | F2 (0.64) | PKMF2NAMPTPGRPOLB | |
| SCHEMBL7364438 | 0.76 | F2 (0.67) | PKMF2PGR | |
| SCHEMBL8547842 | 0.76 | F2 (0.67) | F2NAMPTPGRNR3C1ALDH1A1 | |
| SCHEMBL8549652 | 0.74 | ESR1 (0.66) | PKMPGRMEN1KMT2AS1PR1 | |
| SCHEMBL8544327 | 0.74 | PGR (0.56) | PKMPGRMEN1KMT2AS1PR1 | |
| SCHEMBL8542813 | 0.74 | F2 (0.73) | PKMF2NR3C1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |