Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536852 | 0.85 | ALDH1A1 (0.37) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL5284629 | 0.77 | ALDH1A1 (0.39) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL7132195 | 0.74 | ALDH1A1 (0.38) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL5029772 | 0.74 | SLC1A3 (0.37) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL7765472 | 0.73 | KMT2A (0.36) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9745618 | 0.73 | SLC1A3 (0.36) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL2331142 | 0.69 | ALDH1A1 (0.41) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL7129502 | 0.69 | NPC1 (0.30) | — | |
| SCHEMBL8677682 | 0.68 | TDP1 (0.39) | ALDH1A1MAPT | |
| SCHEMBL28478305 | 0.67 | CES2 (0.42) | MEN1KMT2AALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | claimed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | claimed |