Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FABP7 | O15540 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9745618 | 0.99 | SLC1A3 (0.36) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL9745609 | 0.89 | ALDH1A1 (0.41) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL5284629 | 0.80 | ALDH1A1 (0.39) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL7765472 | 0.79 | KMT2A (0.36) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL23536852 | 0.78 | ALDH1A1 (0.37) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL16759364 | 0.75 | — | — | |
| SCHEMBL8545819 | 0.74 | SLC1A3 (0.35) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL5150393 | 0.72 | KMT2A (0.40) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL2331142 | 0.72 | ALDH1A1 (0.41) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL19285698 | 0.70 | KMT2A (0.37) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951244-A2 | CALCILYTIC COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007062370-A2 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |