SCHEMBL7765472

SCHEMBL7765472

O=C(O)C1C=CC=CC1(Cc1ccccc1)OCc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
SLC1A3 P43003 2/20 0.36
SLC1A2 P43004 2/20 0.36
SLC1A1 P43005 2/20 0.36
MEN1 O00255 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
ALDH1A1 P00352 5/20 0.35
MAPT P10636 2/20 0.34
MAPK1 P28482 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A3 Q01959 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP3A4 P08684 2/20 0.34
HSD11B1 P28845 1/20 0.34
FABP7 O15540 1/20 0.34
FABP5 Q01469 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11419786 0.82 CYP3A4 (0.39) KMT2AMEN1ALDH1A1MAPTCYP3A4
SCHEMBL21526667 0.79 THRB (0.33) KMT2AMEN1ALDH1A1MAPTCYP3A4
SCHEMBL5029772 0.79 SLC1A3 (0.37) KMT2ASLC1A3SLC1A2SLC1A1MEN1
SCHEMBL5284629 0.79 ALDH1A1 (0.39) KMT2ASLC1A3SLC1A2SLC1A1MEN1
SCHEMBL21526675 0.78 CYP3A4 (0.36) KMT2AMEN1ALDH1A1MAPTCYP3A4
Hydrochloric Acid SCHEMBL9745618 0.78 SLC1A3 (0.36) KMT2ASLC1A3SLC1A2SLC1A1MEN1
SCHEMBL23536852 0.77 ALDH1A1 (0.37) KMT2ASLC1A3SLC1A2SLC1A1MEN1
SCHEMBL4216034 0.75 HSD11B1 (0.38) KMT2AMEN1ALDH1A1MAPTCYP3A4
SCHEMBL2160193 0.75 HSD11B1 (0.41) KMT2AMEN1ALDH1A1MAPTCYP3A4
SCHEMBL8545819 0.73 SLC1A3 (0.35) KMT2ASLC1A3SLC1A2SLC1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1105416-A1 NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS Keystone Biomedical, Inc. (US) 2001-06-13 EP claimed
US-6063919-A ESTERIFICATION OF O-DEPROTECTED DIBENZYL EXOCHELIC ACID WITH BENZYL EPI-COBACTIN, HYDROGENOLYTICALLY REMOVING THE THREE BENZYL GROUPS TO FORM EXOCHELIN 786SM(R) KEYSTONE BIOMEDICAL, INC. (US) 2000-05-16 US claimed
WO-2000009547-A1 NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS KEYSTONE BIOMEDICAL, INC. (US) 2000-02-24 WO claimed
EP-1105416-A1 NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS Keystone Biomedical, Inc. (US) 2001-06-13 EP disclosed
US-6063919-A ESTERIFICATION OF O-DEPROTECTED DIBENZYL EXOCHELIC ACID WITH BENZYL EPI-COBACTIN, HYDROGENOLYTICALLY REMOVING THE THREE BENZYL GROUPS TO FORM EXOCHELIN 786SM(R) KEYSTONE BIOMEDICAL, INC. (US) 2000-05-16 US disclosed
WO-2000009547-A1 NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS KEYSTONE BIOMEDICAL, INC. (US) 2000-02-24 WO disclosed