Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.76 |
| ▸ | MAOA | P21397 | 7/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.61 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30398583 | 1.00 | MAOB (0.76) | MAOBMAOAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8545870 | 0.89 | RAB9A (0.71) | MAOBMAOAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL12578130 | 0.85 | MAOB (0.56) | MAOBMAOAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL12578135 | 0.84 | MAOB (0.55) | MAOBMAOAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL9454264 | 0.83 | MAOB (0.89) | MAOBMAOAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL27983208 | 0.83 | RAB9A (0.63) | MAOBMAOAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL13220846 | 0.81 | MAOB (0.76) | MAOBMAOARAB9AFFAR1 | |
| SCHEMBL3423658 | 0.81 | MAOB (0.65) | MAOBMAOARAB9A | |
| SCHEMBL1164139 | 0.81 | MAOB (0.74) | MAOBMAOAALDH1A1RAB9AFFAR1 | |
| SCHEMBL29464145 | 0.81 | MAOB (0.76) | MAOBMAOARAB9APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010818-B | Morpholinamide derivatives and uses thereof | 广东东阳光药业股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| EP-3762364-B1 | PYRROLIDINEAMIDE DERIVATIVES AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-08-23 | — | — | EP | disclosed |
| CN-110240557-B | Pyrrolidine amide derivatives and use thereof | 广东东阳光药业有限公司 | 2023-05-09 | — | — | CN | disclosed |
| US-11225460-B2 | Pyrrolidineamide derivatives and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-01-18 | — | — | US | disclosed |
| CN-108912029-B | Nitrogen-containing heterocyclic amide derivative and use thereof | 广东东阳光药业有限公司 | 2021-10-01 | — | — | CN | disclosed |
| US-20210053918-A1 | PYRROLIDINEAMIDE DERIVATIVES AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-02-25 | — | — | US | disclosed |
| CN-112010818-A | Morpholine amide derivative and application thereof | 广东东阳光药业有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-110240557-A | Pyrrolidine derivative and application thereof | 广东东阳光药业有限公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-108912029-A | Nitrogen-containing heterocycle amide derivatives and application thereof | 广东东阳光药业有限公司 | 2018-11-30 | — | — | CN | disclosed |
| US-9884832-B2 | Inhibitors targeting drug-resistant influenza A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-06 | — | — | US | disclosed |
| US-7968552-B2 | Oxadiazolidinedione compound | ASTELLAS PHARMA INC. (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7968552-B2 | Oxadiazolidinedione compound | ASTELLAS PHARMA INC. (JP) | 2011-06-28 | — | — | US | disclosed |
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | ABBOTT LABORATORIES (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | ABBOTT LABORATORIES (US) | 2010-08-26 | — | — | US | disclosed |
| WO-2010093704-A1 | AGONISTS AND ANTAGONISTS OF THE S1P5 RECEPTOR, AND METHODS OF USES THEREOF | ABBOTT LABORATORIES (US) | 2010-08-19 | — | — | WO | disclosed |
| US-20090186909-A1 | Oxadiazolidinedione Compound | ASTELLAS PHARMA INC. (JP) | 2009-07-23 | — | — | US | disclosed |
| US-20090186909-A1 | Oxadiazolidinedione Compound | ASTELLAS PHARMA INC. (JP) | 2009-07-23 | — | — | US | disclosed |
| US-20090186909-A1 | Oxadiazolidinedione Compound | ASTELLAS PHARMA INC. (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-2011788-A1 | OXADIAZOLIDINEDIONE COMPOUND | Astellas Pharma Inc. (JP) | 2009-01-07 | — | — | EP | disclosed |
| EP-2011788-A1 | OXADIAZOLIDINEDIONE COMPOUND | Astellas Pharma Inc. (JP) | 2009-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186909-A1 | Oxadiazolidinedione Compound | GPR119, GPR39, GPR65 | MAOB 3965/4885MAOA 4379/4885ALDH1A1 3249/4885 |
| US-20100216762-A1 | Agonists and Antagonists of the S1P5 Receptor, and Methods of Use Thereof | S1PR5, LPAR5, S1PR1 | MAOB 2578/4885MAOA 1922/4885ALDH1A1 1328/4885 |
| US-11225460-B2 | Pyrrolidineamide derivatives and uses thereof | MAOB, MAOA, PARK7 | MAOB 1/4885MAOA 2/4885ALDH1A1 1191/4885 |
| US-20210053918-A1 | PYRROLIDINEAMIDE DERIVATIVES AND USES THEREOF | MAOB, MAOA, PARK7 | MAOB 1/4885MAOA 2/4885ALDH1A1 1191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.