Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549933 | 0.86 | ELANE (0.44) | ELANECTRB1 | |
| SCHEMBL6496892 | 0.84 | ELANE (0.60) | ELANECTRB1 | |
| SCHEMBL8545895 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AELANELMNA | |
| SCHEMBL8545278 | 0.79 | ELANE (0.47) | ALDH1A1ELANELMNACTRB1 | |
| SCHEMBL8551382 | 0.79 | ELANE (0.47) | ALDH1A1ELANELMNACTRB1 | |
| SCHEMBL8549203 | 0.77 | TTR (0.41) | ALDH1A1MEN1KMT2AELANEL3MBTL1 | |
| SCHEMBL8546638 | 0.77 | ELANE (0.45) | ALDH1A1KMT2AELANEKDM4ECTRB1 | |
| SCHEMBL10964892 | 0.75 | ELANE (0.72) | ELANECTRB1 | |
| SCHEMBL8545277 | 0.74 | MAPT (0.59) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| Hydrochloric Acid SCHEMBL10961198 | 0.73 | ELANE (0.62) | ELANECTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |