Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 8/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPR3 | P17342 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549203 | 0.87 | TTR (0.41) | ALDH1A1KMT2AMEN1ELANEL3MBTL1 | |
| SCHEMBL8549933 | 0.83 | ELANE (0.44) | ELANECTRB1 | |
| SCHEMBL27493723 | 0.83 | ELANE (0.62) | ELANECTRB1 | |
| SCHEMBL6499915 | 0.83 | ELANE (0.62) | ELANECTRB1 | |
| SCHEMBL8545872 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1ELANEL3MBTL1 | |
| SCHEMBL8545277 | 0.82 | MAPT (0.59) | ALDH1A1KMT2AMEN1LMNAALOX15 | |
| SCHEMBL8545278 | 0.81 | ELANE (0.47) | ALDH1A1ELANECTRB1LMNA | |
| SCHEMBL8551382 | 0.81 | ELANE (0.47) | ALDH1A1ELANECTRB1LMNA | |
| SCHEMBL8546638 | 0.79 | ELANE (0.45) | ALDH1A1KMT2AELANECTRB1 | |
| SCHEMBL8549217 | 0.78 | ELANE (0.41) | ALDH1A1KMT2AMEN1ELANECTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |