Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.49 |
| ▸ | GABRE | P78334 | 1/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 7/20 | 0.47 |
| ▸ | HTR1D | P28221 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885806 | 0.92 | SLC6A4 (0.57) | SLC6A4GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8539366 | 0.80 | HTR1B (0.48) | MAPK1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8885771 | 0.78 | HTR1B (0.59) | SLC6A4GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2182107 | 0.78 | HTR1B (0.76) | HTR1BHTR1DHTR6HTR1A | |
| SCHEMBL29827195 | 0.78 | HTR1B (0.76) | HTR1BHTR1DHTR6HTR1A | |
| SCHEMBL772429 | 0.78 | HTR1B (0.76) | HTR1BHTR1DHTR6HTR1A | |
| SCHEMBL697582 | 0.78 | HTR1B (0.76) | HTR1BHTR1DHTR6HTR1A | |
| SCHEMBL8916752 | 0.76 | HTR6 (0.49) | SLC6A4HTR1BHTR1DHTR6HTR1A | |
| SCHEMBL8888890 | 0.75 | HTR1B (0.60) | SLC6A4HTR1BHTR1DHTR6HTR1A | |
| SCHEMBL8979735 | 0.74 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785933-B1 | INDOLE DERIVATIVES AS 5HT1-LIKE AGONISTS | PFIZER LTD (GB) | 1998-03-11 | — | — | EP | disclosed |