Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825262 | 0.93 | KMT2A (0.39) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL7818383 | 0.93 | LMNA (0.37) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL7817749 | 0.93 | LMNA (0.37) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL594052 | 0.83 | VDR (0.54) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL8542539 | 0.78 | LMNA (0.41) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL9194706 | 0.77 | KMT2A (0.43) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL10624562 | 0.76 | MEN1 (0.58) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL8545767 | 0.76 | MAOA (0.41) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL10619779 | 0.74 | DHODH (0.44) | LMNAMAPK1KMT2AGAAMEN1 | |
| SCHEMBL29044851 | 0.73 | VDR (0.54) | LMNAMAPK1KMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639183-B1 | NITROGEN OXIDES OF AZA- AND DIAZA-ANTHRACENEDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | BOEHRINGER MANNHEIM ITALIA (IT) | 1998-07-01 | — | — | EP | disclosed |