Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.54 |
| ▸ | RXRB | P28702 | 8/20 | 0.54 |
| ▸ | RXRG | P48443 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508804 | 0.97 | RXRA (0.54) | RXRARXRBRXRGLMNASMN1; SMN2 | |
| SCHEMBL2876699 | 0.86 | RXRA (0.54) | RXRARXRBRXRGSMN1; SMN2MRGPRX4 | |
| SCHEMBL13768229 | 0.85 | RXRA (0.57) | RXRARXRBRXRGLMNASMN1; SMN2 | |
| SCHEMBL3478697 | 0.85 | RXRA (0.51) | RXRARXRBRXRGMRGPRX4PRMT5 | |
| SCHEMBL3479749 | 0.83 | RXRB (0.66) | RXRARXRBRXRGMRGPRX4KDM4E | |
| SCHEMBL28548896 | 0.82 | RXRB (0.64) | RXRARXRBRXRGMRGPRX4KDM4E | |
| SCHEMBL9017314 | 0.81 | MTNR1A (0.50) | — | |
| SCHEMBL23252533 | 0.79 | S1PR5 (0.52) | RXRARXRBRXRGLMNAMRGPRX4 | |
| SCHEMBL23874594 | 0.79 | S1PR5 (0.52) | RXRARXRBRXRGLMNAMRGPRX4 | |
| SCHEMBL7663445 | 0.79 | MRGPRX4 (0.56) | SMN1; SMN2MRGPRX4KDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842161-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-20 | — | — | EP | disclosed |