Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786262 | 0.80 | LTA4H (0.52) | SLC2A1ACACBACACASMN1; SMN2L3MBTL1 | |
| SCHEMBL6254887 | 0.74 | CYP3A4 (0.46) | SMN1; SMN2CYP3A4PPARAGAAL3MBTL1 | |
| SCHEMBL27819494 | 0.72 | L3MBTL1 (0.46) | TDP1PPARAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL28128014 | 0.71 | L3MBTL1 (0.45) | TDP1PPARAPOLBL3MBTL1 | |
| SCHEMBL23539455 | 0.70 | APP (0.45) | SMN1; SMN2CYP3A4PPARA | |
| SCHEMBL6893076 | 0.69 | CYP3A4 (0.46) | SMN1; SMN2CYP3A4PPARAGAAL3MBTL1 | |
| SCHEMBL8546797 | 0.69 | MAPT (0.47) | SLC2A1L3MBTL1 | |
| SCHEMBL8546355 | 0.69 | ALDH1A1 (0.45) | SMN1; SMN2CYP3A4GAA | |
| SCHEMBL6255661 | 0.69 | HRH3 (0.49) | SMN1; SMN2CYP3A4PPARAGAAL3MBTL1 | |
| SCHEMBL21585201 | 0.69 | AOC3 (0.55) | SLC2A1TDP1CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |