Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543586 | 0.94 | RAB9A (0.51) | RAB9ACYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL8541119 | 0.88 | SMN1; SMN2 (0.44) | RAB9ACYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL9382429 | 0.86 | SMN1; SMN2 (0.43) | RAB9ACYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL8548239 | 0.86 | AURKA (0.44) | RAB9ACYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL8547543 | 0.83 | HTT (0.34) | RAB9ACYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL8547041 | 0.83 | KCNH2 (0.36) | RAB9AKDM4ESMN1; SMN2TSHRHTT | |
| SCHEMBL8542280 | 0.83 | AURKA (0.47) | RAB9ACYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL8544014 | 0.80 | ELOVL1 (0.39) | RAB9ACYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL8542741 | 0.80 | RAB9A (0.78) | RAB9ACYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL8541239 | 0.80 | KCNH2 (0.38) | RAB9AKDM4ESMN1; SMN2TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |