Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547249 | 0.94 | AURKA (0.45) | AURKARPS6KB1RAB9ATSHRNPC1 | |
| SCHEMBL8547620 | 0.86 | RAB9A (0.50) | AURKARPS6KB1RAB9ATSHRNPC1 | |
| SCHEMBL9383256 | 0.85 | TRPA1 (0.39) | AURKARPS6KB1RAB9APPARGKDM4E | |
| SCHEMBL8548719 | 0.85 | MRGPRX1 (0.40) | AURKARPS6KB1RAB9ATSHRNPC1 | |
| SCHEMBL8546847 | 0.85 | RAB9A (0.41) | AURKARPS6KB1RAB9ATSHRNPC1 | |
| SCHEMBL8548684 | 0.83 | RAB9A (0.42) | AURKARPS6KB1RAB9ATSHRNPC1 | |
| SCHEMBL9389676 | 0.83 | AURKA (0.41) | AURKARPS6KB1LTA4HEPHX2 | |
| SCHEMBL8548285 | 0.81 | GABRA1 (0.39) | AURKARPS6KB1RAB9ATSHRNPC1 | |
| SCHEMBL8540692 | 0.81 | RAB9A (0.65) | AURKARPS6KB1RAB9ATSHRNPC1 | |
| SCHEMBL8547041 | 0.81 | KCNH2 (0.36) | AURKARPS6KB1RAB9ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |