Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.36 |
| ▸ | AURKA | O14965 | 3/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548684 | 0.88 | RAB9A (0.42) | LMNAPOLBKDM4ERAB9AALDH1A1 | |
| SCHEMBL8542280 | 0.87 | AURKA (0.47) | ELOVL1POLBKDM4ERAB9AALDH1A1 | |
| SCHEMBL8548181 | 0.87 | TRPA1 (0.43) | ELOVL1LMNAPOLBRAB9ANPC1 | |
| SCHEMBL8543586 | 0.86 | RAB9A (0.51) | ELOVL1LMNAPOLBKDM4ERAB9A | |
| SCHEMBL8541261 | 0.86 | ELOVL1 (0.36) | ELOVL1LMNAPOLBKDM4ERAB9A | |
| SCHEMBL8545027 | 0.86 | ELOVL1 (0.36) | ELOVL1LMNAPOLBKDM4ERAB9A | |
| SCHEMBL8548285 | 0.86 | GABRA1 (0.39) | ELOVL1LMNAPOLBKDM4ERAB9A | |
| SCHEMBL8541119 | 0.85 | SMN1; SMN2 (0.44) | LMNAPOLBKDM4ERAB9AALDH1A1 | |
| SCHEMBL8547249 | 0.84 | AURKA (0.45) | LMNAPOLBRAB9ANPC1RPS6KB1 | |
| SCHEMBL9382429 | 0.83 | SMN1; SMN2 (0.43) | LMNAPOLBKDM4ERAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5411963-A | Plant fungicides, miticides, insecticides | DOWELANCO (US) | 1995-05-02 | — | — | US | disclosed |
| EP-0326329-A2 | Quinazoline derivatives | DowElanco (US) | 1989-08-02 | — | — | EP | disclosed |