SCHEMBL362234

SCHEMBL362234

O=C(c1ccco1)N(CCO)CCO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
POLB P06746 6/20 0.50
L3MBTL1 Q9Y468 4/20 0.50
MAPT P10636 4/20 0.50
RECQL P46063 4/20 0.50
PKM P14618 3/20 0.50
KDM4E B2RXH2 2/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
RAB9A P51151 1/20 0.50
GFER P55789 1/20 0.48
LMNA P02545 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
HPGD P15428 2/20 0.47
BLM P54132 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
USP2 O75604 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28403232 0.84 ALDH1A1 (0.42) ALDH1A1POLBL3MBTL1MAPTRECQL
SCHEMBL14640214 0.84 TP53 (0.55) ALDH1A1POLBL3MBTL1MAPTRECQL
SCHEMBL8547801 0.82 BRD4 (0.50) ALDH1A1POLBMAPTCES2CES1
SCHEMBL743702 0.81 ALDH1A1 (0.52) ALDH1A1POLBL3MBTL1MAPTRECQL
SCHEMBL2169988 0.79 POLB (0.55) ALDH1A1POLBL3MBTL1MAPTRECQL
SCHEMBL18421001 0.79 L3MBTL1 (0.49) ALDH1A1POLBL3MBTL1MAPTRECQL
SCHEMBL14802220 0.79 ALDH1A1 (0.70) ALDH1A1POLBL3MBTL1MAPTRECQL
SCHEMBL13381401 0.76 ALDH1A1 (0.43) ALDH1A1POLBL3MBTL1MAPTRAB9A
SCHEMBL14175024 0.75 KDM4E (0.60) ALDH1A1POLBL3MBTL1MAPTRECQL
SCHEMBL23521363 0.74 POLB (0.50) ALDH1A1POLBL3MBTL1MAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12516147-B2 Aldimines and uses thereof BOSTIK SA (FR) 2026-01-06 US disclosed
EP-4077273-B1 ALDIMINES AND USES THEREOF BOSTIK SA (FR) 2025-04-02 EP disclosed
US-20230038642-A1 ALDIMINES AND USES THEREOF BOSTIK SA (FR) 2023-02-09 US disclosed
EP-4077273-A1 ALDIMINES AND USES THEREOF Bostik SA (FR) 2022-10-26 EP disclosed
CN-112898734-B Liquid crystal polymer interlocking network and preparation method and application thereof 中山大学 2022-03-15 CN disclosed
WO-2021122594-A1 ALDIMINES AND USES THEREOF BOSTIK SA (FR) 2021-06-24 WO disclosed
EP-3838891-A1 ALDIMINES AND USES THEREOF BOSTIK SA (FR) 2021-06-23 EP disclosed
CN-112898734-A Liquid crystal polymer interlocking network and preparation method and application thereof 中山大学 2021-06-04 CN disclosed
EP-3510994-A1 PHARMACEUTICAL FORMULATION COMPRISING AN AQUEOUS SUSPENSION OF AN ANDROSTANE DERIVATIVE FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC CONDITIONS GLAXO GROUP LIMITED (GB) 2019-07-17 EP disclosed
EP-1478340-B1 Pharmaceutical formulation comprising an aqueous suspension of an androstane derivative for the treatment of inflammatory and allergic conditions GLAXO GROUP LTD (GB) 2018-09-12 EP disclosed
WO-2003066036-A1 PHARMACEUTICAL FORMULATION FOR ADMINISTRATION BY INHALATION COMPRISING AN ANDROSTANE DERIVATIVE AND A BETA-2-ADRENORECEPTOR FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC CONDITIONS GLAXO GROUP LIMITED (GB) 2003-08-14 WO disclosed
WO-2003066063-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING 17ALPHA-FURANYLESTERS OF 17BETA-CARBOTHIOATE ANDROSTANES WITH A MUSCARINIC RECEPTOR ANTAGONIST GLAXO GROUP LIMITED (GB) 2003-08-14 WO disclosed
WO-2003066032-A1 FORMULATIONS FOR INHALATION GLAXO GROUP LIMITED (GB) 2003-08-14 WO disclosed
US-20030144257-A1 Novel anti-inflammatory androstane derivative compositions GLAXOSMITHKLINE INTELLECTUAL PROPERTY MANAGEMENT LIMITED (GB) 2003-07-31 US disclosed
US-20030109511-A1 Novel anti-inflammatory androstane derivative compositions GLAXOSMITHKLINE INTELLECTUAL PROPERTY MANAGEMENT LIMITED (GB) 2003-06-12 US disclosed
EP-1305329-A1 6.ALPHA.,9.ALPHA.-DIFLUORO-17.ALPHA.-[(2-FURANYLCARBOXYL)OXY]-11.BETA.-HYDROXY-16.ALPHA.-METHYL-3-OXO-ANDROST-1,4,-DIENE-17-CARBOTHIOIC ACID S-FLUOROMETHYL ESTER AS AN ANTI-INFLAMMATORY AGENT GLAXO GROUP LIMITED (GB) 2003-05-02 EP disclosed
US-20020177581-A1 Novel anti-inflammatory androstane derivative GLAXOSMITHKLINE INTELLECTUAL PROPERTY MANAGEMENT LIMITED (GB) 2002-11-28 US disclosed
US-20020173496-A1 Formulation containing novel anti-inflammatory androstane derivative GLAXOSMITHKLINE INTELLECTUAL PROPERTY MANAGEMENT LIMITED (GB) 2002-11-21 US disclosed
US-20020165211-A1 Formulation containing anti-inflammatory androstane derivative GLAXOSMITHKLINE INTELLECTUAL PROPERTY MANAGEMENT LIMITED (GB) 2002-11-07 US disclosed
WO-2002012265-A1 6.ALPHA., 9.ALPHA.-DIFLUORO-17.ALPHA.-`(2-FURANYLCARBOXYL) OXY!-11.BETA.-HYDROXY-16.ALPHA.-METHYL-3-OXO-ANDROST-1,4,-DIENE-17-CARBOTHIOIC ACID S-FLUOROMETHYL ESTER AS AN ANTI-INFLAMMATORY AGENT GLAXO GROUP LIMITED (GB) 2002-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020173496-A1 Formulation containing novel anti-inflammatory androstane derivative NR5A1, IL1A, CYP17A1 ALDH1A1 339/4885POLB 1604/4885L3MBTL1 4872/4885
US-20020165211-A1 Formulation containing anti-inflammatory androstane derivative NR5A1, HSD17B11, CYP17A1 ALDH1A1 391/4885POLB 2593/4885L3MBTL1 4851/4885
US-20030109511-A1 Novel anti-inflammatory androstane derivative compositions NR5A1, CYP17A1, CYP19A1 ALDH1A1 1173/4885POLB 3208/4885L3MBTL1 4862/4885
US-20020177581-A1 Novel anti-inflammatory androstane derivative NR5A1, IL1R1, ADRB1 ALDH1A1 525/4885POLB 2692/4885L3MBTL1 4754/4885
US-20030144257-A1 Novel anti-inflammatory androstane derivative compositions NR5A1, CYP17A1, CYP19A1 ALDH1A1 1151/4885POLB 3115/4885L3MBTL1 4857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.