Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543606 | 0.83 | KEAP1 (0.40) | ALDH1A1KDM4EPOLBTDP1NPC1 | |
| SCHEMBL8545244 | 0.78 | ALDH1A1 (0.37) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9315436 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1MEN1KMT2AGABRPGABRD | |
| SCHEMBL8658096 | 0.71 | KDM4E (0.41) | ALDH1A1MEN1KMT2AGABRPGABRD | |
| SCHEMBL8543238 | 0.70 | TSHR (0.55) | SMN1; SMN2 | |
| SCHEMBL10465634 | 0.70 | GABRP (0.44) | ALDH1A1MEN1KMT2AGABRPGABRD | |
| SCHEMBL8544532 | 0.69 | KDM4E (0.40) | MAPTALDH1A1KMT2AGABRPGABRD | |
| SCHEMBL9077344 | 0.68 | SORT1 (0.44) | ALDH1A1MEN1KMT2AGABRPGABRD | |
| SCHEMBL2807041 | 0.68 | GABRP (0.47) | MAPTALDH1A1MEN1KMT2AGABRP | |
| SCHEMBL8541967 | 0.68 | KDM4E (0.38) | ALDH1A1MEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434965-B1 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID CO (US) | 1998-05-20 | — | — | EP | claimed |