Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31436355 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TSHRKDM4EGAAMAPT | |
| SCHEMBL28965796 | 0.90 | DHODH (0.44) | ALDH1A1TSHRKDM4EGAAMAPT | |
| SCHEMBL29619789 | 0.90 | DHODH (0.44) | ALDH1A1TSHRKDM4EGAAMAPT | |
| SCHEMBL23517141 | 0.89 | SMN1; SMN2 (0.40) | ALDH1A1TSHRKDM4EGAAMAPT | |
| SCHEMBL28280234 | 0.88 | KDM4E (0.41) | ALDH1A1TSHRKDM4EGAAMAPT | |
| SCHEMBL31220981 | 0.87 | KDM4E (0.41) | ALDH1A1TSHRKDM4EGAAMAPT | |
| SCHEMBL30738741 | 0.87 | CYP4F2 (0.46) | ALDH1A1TSHRKDM4EGAAMAPT | |
| SCHEMBL2389957 | 0.87 | KDM4E (0.41) | ALDH1A1TSHRKDM4EGAAMAPT | |
| SCHEMBL2391237 | 0.87 | CYP4F2 (0.46) | ALDH1A1TSHRKDM4EGAAMAPT | |
| SCHEMBL18681199 | 0.87 | LOXL2 (0.45) | ALDH1A1TSHRKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415767-A2 | Process for preparing pyridine carboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1991-03-06 | — | — | EP | claimed |
| CN-119306660-A | Refining method of imazethapyr intermediate | 江苏省农用激素工程技术研究中心有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-114644565-B | Synthesis method of key intermediate of imidazolinone compound | 江苏中旗科技股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-114644565-A | Synthesis method of key intermediate of imidazolone compound | 江苏中旗科技股份有限公司 | 2022-06-21 | — | — | CN | disclosed |
| US-10858320-B2 | Process for manufacturing substituted 5-methoxymethylpyridine-2,3-dicarboxylic acid derivatives | BASF AGROCHEMICAL PRODUCTS B.V. (NL) | 2020-12-08 | — | — | US | disclosed |
| US-9891235-B2 | Pathway specific assays for predicting irritable bowel syndrome diagnosis | NESTEC S.A. (CH) | 2018-02-13 | — | — | US | disclosed |
| US-20170226060-A1 | Process for Manufacturing Substituted 5-Methoxymethylpyridine-2,3-Dicarboxylic Acid Derivatives | BASF AGROCHEMICAL PRODUCTS B.V. (PR) | 2017-08-10 | — | — | US | disclosed |
| US-20170226060-A1 | Process for Manufacturing Substituted 5-Methoxymethylpyridine-2,3-Dicarboxylic Acid Derivatives | BASF AGROCHEMICAL PRODUCTS B.V. (PR) | 2017-08-10 | — | — | US | disclosed |
| US-20160130279-A1 | PATHWAY SPECIFIC ASSAYS FOR PREDICTING IRRITABLE BOWEL SYNDROME DIAGNOSIS | NESTEC S.A. (CH) | 2016-05-12 | — | — | US | disclosed |
| US-20160130279-A1 | PATHWAY SPECIFIC ASSAYS FOR PREDICTING IRRITABLE BOWEL SYNDROME DIAGNOSIS | NESTEC S.A. (CH) | 2016-05-12 | — | — | US | disclosed |
| US-20110224433-A1 | Process for Manufacturing Substituted 3-pyridylmethyl Ammonium Bromides | BASF SE (DE) | 2011-09-15 | — | — | US | disclosed |
| EP-0588372-B1 | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL IND CO LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-0588372-A1 | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5252739-A | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL IND. CO., LTD. (JP) | 1993-10-12 | — | — | US | disclosed |
| US-5175300-A | Reacting a halo-oxalactic ester with 2-propenal and ammonia; cyclization | SUGAI CHEMICAL IND. CO., LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0220518-B1 | PREPARATION OF SUBSTITUTED AND DISUBSTITUTED PYRIDINE-2,3-DICARBOXYLATE ESTERS | AMERICAN CYANAMID COMPANY (US) | 1991-02-06 | — | — | EP | disclosed |
| EP-0357792-A1 | PROCESS FOR PREPARING PYRIDINE-2,3-DICARBOXYLIC ACID COMPOUNDS | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-03-14 | — | — | EP | disclosed |
| EP-0292032-A1 | Process for the preparation of pyridine-2,3-dicarboxylic acid derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-11-23 | — | — | EP | disclosed |
| US-4723011-A | ALPHA-HALO-BETA-KETOESTERS, ALPHA, BETA UNSATURATED KETONE OR ALDEHYDE, AMMONIUM SALT | AMERICAN CYANAMID COMPANY (US) | 1988-02-02 | — | — | US | disclosed |
| EP-0220518-A2 | Preparation of substituted and disubstituted pyridine-2,3-dicarboxylate esters | AMERICAN CYANAMID COMPANY (US) | 1987-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224433-A1 | Process for Manufacturing Substituted 3-pyridylmethyl Ammonium Bromides | NCOR2, NCOR1, CBR3 | ALDH1A1 2991/4885TSHR 300/4885KDM4E 1043/4885 |
| US-20170226060-A1 | Process for Manufacturing Substituted 5-Methoxymethylpyridine-2,3-Dicarboxylic Acid Derivatives | DDT, DDC, CYP4X1 | ALDH1A1 79/4885TSHR 3983/4885KDM4E 183/4885 |
| US-20160130279-A1 | PATHWAY SPECIFIC ASSAYS FOR PREDICTING IRRITABLE BOWEL SYNDROME DIAGNOSIS | FABP2, TPH2, TPH1 | ALDH1A1 3209/4885TSHR 1681/4885KDM4E 4546/4885 |
| US-10858320-B2 | Process for manufacturing substituted 5-methoxymethylpyridine-2,3-dicarboxylic acid derivatives | DDT, DDC, CYP4X1 | ALDH1A1 79/4885TSHR 3983/4885KDM4E 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.