Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333684 | 0.86 | ESR1 (0.62) | ESR1MEN1KMT2APGRALDH1A1 | |
| SCHEMBL8544327 | 0.84 | PGR (0.56) | ESR1MEN1KMT2APGRALDH1A1 | |
| SCHEMBL7326459 | 0.81 | PGR (0.62) | ESR1MEN1KMT2APGRALDH1A1 | |
| SCHEMBL27593108 | 0.80 | ESR1 (1.00) | ESR1MEN1KMT2APGRALDH1A1 | |
| SCHEMBL7326995 | 0.80 | NR3C1 (0.58) | ESR1MEN1KMT2APGRALDH1A1 | |
| SCHEMBL7332305 | 0.79 | PGR (0.55) | ESR1MEN1KMT2APGRALDH1A1 | |
| SCHEMBL7334051 | 0.79 | MEN1 (0.54) | ESR1MEN1KMT2APGRALDH1A1 | |
| SCHEMBL5330652 | 0.77 | ESR1 (0.78) | ESR1MEN1KMT2APGRALDH1A1 | |
| SCHEMBL7332897 | 0.77 | KDM4E (0.52) | PGRLMNAS1PR1L3MBTL1HTT | |
| SCHEMBL6295367 | 0.77 | ESR1 (0.88) | ESR1MEN1KMT2APGRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046710-C | New 4-aminopyridines, process for preparing the same and medicaments containing the same | LUOHE DIAGNOSTIC EQUIPMENT CO (DE) | 1999-11-24 | — | — | CN | disclosed |
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| CN-1119858-A | Aminopyridines, process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1996-04-03 | — | — | CN | disclosed |