Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 16/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 16/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548355 | 0.85 | DRD2 (0.47) | DRD2HTR2ADRD3 | |
| SCHEMBL7484169 | 0.85 | HTR1D (0.49) | DRD2 | |
| SCHEMBL30908856 | 0.85 | HTR1D (0.49) | DRD2 | |
| SCHEMBL8703766 | 0.78 | UBE2M (0.44) | UBE2MDCUN1D1 | |
| SCHEMBL8550256 | 0.77 | UBE2M (0.49) | UBE2MDCUN1D1DRD2HTR2ADRD3 | |
| SCHEMBL8552426 | 0.77 | RORC (0.49) | DRD2HTR2ADRD3 | |
| Phenyl Propionic Acid SCHEMBL8703758 | 0.77 | UBE2M (0.47) | UBE2MDCUN1D1 | |
| SCHEMBL8549309 | 0.76 | UBE2M (0.39) | UBE2MDCUN1D1DRD2 | |
| SCHEMBL8548767 | 0.75 | UBE2M (0.52) | UBE2MDCUN1D1 | |
| SCHEMBL7481601 | 0.74 | HTR1D (0.48) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |