Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 14/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552432 | 0.85 | RORC (0.51) | RORCACKR3DRD2HTR2ADRD3 | |
| SCHEMBL8552391 | 0.84 | RORC (0.49) | RORCACKR3CCR2L3MBTL1HTR1A | |
| SCHEMBL7483530 | 0.84 | RORC (0.68) | RORCDRD2HTR1AHTR1BHTR1F | |
| SCHEMBL8551104 | 0.80 | UBE2M (0.46) | HTR1AHTR1BHTR1F | |
| SCHEMBL8387441 | 0.78 | RORC (0.51) | RORCCNR1 | |
| SCHEMBL8548353 | 0.77 | UBE2M (0.40) | DRD2HTR2ADRD3 | |
| SCHEMBL8703766 | 0.76 | UBE2M (0.44) | — | |
| Phenyl Propionic Acid SCHEMBL8548350 | 0.76 | UBE2M (0.46) | — | |
| SCHEMBL8549309 | 0.76 | UBE2M (0.39) | DRD2 | |
| SCHEMBL8548604 | 0.76 | HTR1F (0.46) | DRD2HTR2ADRD3HTR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |