Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550098 | 0.88 | MEN1 (0.39) | MEN1KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL8548840 | 0.86 | KDM4E (0.35) | MEN1KMT2AALDH1A1LMNAUSP2 | |
| SCHEMBL8548495 | 0.84 | MEN1 (0.35) | MEN1KMT2AALDH1A1LMNAUSP2 | |
| SCHEMBL8550091 | 0.83 | MEN1 (0.38) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9318344 | 0.76 | CYP4F2 (0.36) | KMT2AHTT | |
| SCHEMBL8549281 | 0.75 | KDM4E (0.35) | MEN1KMT2AALDH1A1LMNANPC1 | |
| SCHEMBL9320112 | 0.74 | SLC6A3 (0.43) | KMT2AALDH1A1LMNAUSP2NPC1 | |
| SCHEMBL8549279 | 0.70 | KDM4E (0.43) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL8548832 | 0.70 | KDM4E (0.44) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL16968516 | 0.68 | TACR1 (0.47) | MEN1KMT2AALDH1A1USP2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514198-B1 | 1H-Imidazol-1-yl-methyl benzofuran derivatives with the imidazolyl moiety being substituted by a cycloalkyl group | GLAXO GROUP LTD (GB) | 1998-08-05 | — | — | EP | disclosed |
| US-5498722-A | HYPOTENSIVES | GLAXO GROUP (GB) | 1996-03-12 | — | — | US | disclosed |
| US-5332831-A | Angiotensin antagonist | GLAXO GROUP LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |
| EP-0514198-A1 | 1H-Imidazol-1-yl-methyl benzofuran derivatives with the imidazolyl moiety being substituted by a cycloalkyl group | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |