Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324406 | 0.86 | KMO (0.33) | KMOGRM4 | |
| SCHEMBL9027404 | 0.85 | P2RX7 (0.31) | CNR2P2RX7KMOCTNNB1WNT3A | |
| SCHEMBL8548980 | 0.82 | ACP3 (0.38) | ACP3CNR2P2RX7TNFADAMTS5 | |
| SCHEMBL4595530 | 0.76 | ULK1 (0.34) | P2RX7CTNNB1WNT3ARXFP1ALDH1A1 | |
| SCHEMBL8328817 | 0.75 | — | — | |
| SCHEMBL6152914 | 0.75 | PDE2A (0.36) | P2RX7KMOCYP2C19 | |
| SCHEMBL30903830 | 0.75 | ACP3 (0.50) | ACP3CNR2P2RX7TDP1ALDH1A1 | |
| SCHEMBL9776265 | 0.75 | ACP3 (0.50) | ACP3CNR2P2RX7TDP1ALDH1A1 | |
| SCHEMBL8546018 | 0.71 | TNF (0.38) | ACP3CNR2P2RX7TNFHSD17B10 | |
| SCHEMBL12317610 | 0.70 | ACP3 (0.44) | ACP3CNR2SCDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695292-B1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LTD (GB) | 1998-02-25 | — | — | EP | disclosed |
| US-5585327-A | PRE- AND POST-EMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1996-12-17 | — | — | US | disclosed |
| CN-1124024-A | Herbicidal (4-substituted pyridyl)-3-carbinols | ZENECA LTD (GB) | 1996-06-05 | — | — | CN | disclosed |
| EP-0695292-A1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LIMITED (GB) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994024106-A1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LIMITED (GB) | 1994-10-27 | — | — | WO | disclosed |
| US-5308826-A | Pre- and postemergence herbicides; controlling weeds, particularly broad leaf plants and grasses | ZENECA LIMITED (GB) | 1994-05-03 | — | — | US | disclosed |