Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14064554 | 0.77 | CYP3A4 (0.45) | CYP3A4ACHEHPGDCA12CA1 | |
| SCHEMBL29116936 | 0.75 | POLB (0.38) | CYP3A4ACHEHPGDCA12CA1 | |
| SCHEMBL9041942 | 0.74 | CYP3A4 (0.41) | CYP3A4ACHEHPGDCA12CA1 | |
| SCHEMBL26604869 | 0.73 | CYP3A4 (0.47) | CYP3A4ACHEHPGDCA12CA1 | |
| SCHEMBL643290 | 0.72 | LMNA (0.56) | CYP3A4HPGDCA12CA1CA2 | |
| SCHEMBL1375730 | 0.70 | APP (0.38) | CYP3A4ACHEHPGDCA12CA1 | |
| SCHEMBL7409024 | 0.69 | GAA (0.43) | HPGDKDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL2599610 | 0.69 | ALDH1A1 (0.40) | HPGDKDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL1933140 | 0.69 | PTGES (0.58) | CYP3A4HPGDPOLBALOX5PTGS1 | |
| SCHEMBL3961509 | 0.69 | CA12 (0.47) | CYP3A4HPGDCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877297-A | Boronic compound complexing reagents and highly stable complexes | PROLINX, INC. (US) | 1999-03-02 | — | — | US | disclosed |