Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 8/20 | 0.44 |
| ▸ | IKBKB | O14920 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100319 | 0.89 | PTGER1 (0.49) | PTGER1PTGS2 | |
| SCHEMBL8548972 | 0.81 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL8548707 | 0.79 | ENPP3 (0.57) | PTGS2ENPP3ENPP1 | |
| SCHEMBL8546693 | 0.77 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL8552225 | 0.77 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL8551355 | 0.76 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL8547371 | 0.76 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL8552226 | 0.75 | PTGS2 (0.47) | PTGS2PTGS1ENPP3ENPP1 | |
| SCHEMBL9098556 | 0.75 | PTGS2 (0.38) | PTGS2PTGS1 | |
| SCHEMBL8549867 | 0.75 | PTGS2 (0.38) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036617-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | disclosed |