Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.57 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.57 |
| ▸ | GHSR | Q92847 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100314 | 0.84 | ENPP3 (0.50) | ENPP3ENPP1GHSRTP53THRB | |
| SCHEMBL9100319 | 0.83 | PTGER1 (0.49) | GHSRPTGS2 | |
| SCHEMBL8548710 | 0.79 | PTGER1 (0.44) | ENPP3ENPP1PTGS2 | |
| SCHEMBL8551355 | 0.78 | PTGS2 (0.50) | HPGDS1PR1S1PR3PTGS2KMT2A | |
| SCHEMBL8551014 | 0.78 | PTGS2 (0.41) | TP53THRBPOLBPTGS2LMNA | |
| SCHEMBL13666252 | 0.78 | GHSR (0.60) | GHSRCA12CA1CA2CA4 | |
| SCHEMBL8551030 | 0.77 | TP53 (0.43) | TP53THRBPTGS2LMNA | |
| SCHEMBL8552226 | 0.77 | PTGS2 (0.47) | ENPP3ENPP1TP53THRBPOLB | |
| SCHEMBL11266317 | 0.77 | CA12 (0.70) | GHSRCA12CA1CA2CA4 | |
| SCHEMBL8547371 | 0.76 | PTGS2 (0.47) | TP53THRBPTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036617-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | disclosed |